|
|
2-imino-3-(indol-3-yl)propanoate + H2O2 <=> N-[2-(carboxylatoamino)-1,2-bis(1H-indol-3-yl)ethyl]carbamate + H2O
|
1.21.98.2
dichlorochromopyrrolate synthase
|
–
|
| |
MetaCyc:
RXN-18167
|
|
|
|
N-[2-(carboxylatoamino)-1,2-bis(1H-indol-3-yl)ethyl]carbamate + H+ <=> Chromopyrrolate + NH3
|
not assigned
|
–
|
| |
MetaCyc:
RXN-18168
|
|
|
|
holyrine_B <=> 3''-O-demethyl-4''-N-demethyl-staurosporine + H2O
|
not assigned
|
–
|
| |
MetaCyc:
RXN-10930
|
|
|
|
S-adenosyl-L-methionine + 3''-O-demethyl-staurosporine <=> staurosporine + S-adenosyl-L-homocysteine + H+
|
2.1.1.139
3'-demethylstaurosporine O-methyltransferase
|
–
|
| |
BRENDA:
BR29466
KEGG:
R05757
MetaCyc:
2.1.1.139-RXN
|
|
|
|
staurosporine_aglycone + dTDP-L-ristosamine <=> H+ + Holyrine_A + dTDP
|
2.4
2.4.1
|
–
–
|
| |
KEGG:
R11122
MetaCyc:
RXN-10931
|
|
|
|
L-tryptophan + O2 <=> H+ + 2-imino-3-(indol-3-yl)propanoate + H2O2
|
1.4.3
1.4.3.23
7-chloro-L-tryptophan oxidase
|
–
–
|
| |
BRENDA:
BS440306
KEGG:
R11119
MetaCyc:
RXN-10922
|
|
|
|
Holyrine_A + O2 + reduced_acceptor <=> holyrine_B + H2O + acceptor
|
not assigned
|
–
|
| |
MetaCyc:
RXN-10932
|
|
|
|
S-adenosyl-L-methionine + 3''-O-demethyl-4''-N-demethyl-staurosporine <=> 3''-O-demethyl-staurosporine + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN-10929
|
|
|
|
Chromopyrrolate + O2 + NADH + H+ <=> staurosporine_aglycone + CO2 + H2O + NAD+
|
1.13.12
|
–
|
| |
KEGG:
R11121
MetaCyc:
RXN-10924
|
|
